Pharmaceutical Sealing Solutions
Hygienic & High-Performance
Seals for Pharmaceutical Applications
At Ashton Seals, we supply
high-performance sealing solutions for the pharmaceutical industry, designed to
meet strict hygiene, safety and regulatory requirements. From drug manufacturing and
processing to sterile filling and packaging systems, our seals deliver contamination
control, chemical resistance and long-term reliability in critical applications.
Sealing Solutions for Pharmaceutical Systems
We provide sealing solutions for a wide range of
pharmaceutical applications including:
Drug manufacturing and processing equipment
Cleanroom and sterile environments
Filling, dosing, and packaging systems
Biopharmaceutical and laboratory equipment
Pumps, valves and fluid handling systems
These systems require precision-engineered seals that
maintain purity and prevent contamination at every stage of production.
Hygiene, Cleanroom & Contamination Control
In pharmaceutical manufacturing, maintaining absolute
cleanliness and product integrity is essential.
Sealing solutions must:
Prevent ingress of contaminants and bacteria
Minimise particle generation and extractables
Be suitable for cleanroom environments
Withstand sterilisation processes such as CIP
(Clean-in-Place) and SIP (Steam-in-Place)
Failures in sealing can compromise product safety, making seal
performance critical to compliance and patient safety.
Pharmaceutical Standards & Certifications
Sealing solutions used in pharmaceutical environments must
meet strict global standards:
Key Pharmaceutical Certifications
FDA (Food & Drug Administration) – ensures material
safety and suitability for contact applications
USP Class VI – highest standard for biocompatibility and low
toxicity
EU Regulation 1935/2004 – materials in contact with
consumables
Additional Requirements
GMP (Good Manufacturing Practice) compliance
Full material traceability and documentation
Low extractables and leachables
Cleanroom manufacturing capabilities
These standards ensure sealing components are safe,
compliant and suitable for pharmaceutical production environments.
Products for Pharmaceutical Applications
We supply a comprehensive range of sealing products for
pharmaceutical systems including:
These products are widely used across processing equipment, sterile systems and fluid transfer applications.
Materials & Performance
Pharmaceutical sealing solutions must be manufactured from materials that meet strict performance and compliance requirements.
We offer materials that provide:
Resistance to aggressive chemicals and cleaning agents
Compatibility with sterilisation processes (CIP/SIP)
Low levels of extractables and contamination risk
Stability across temperature and pressure variations
Common materials include:
PTFE – excellent chemical resistance and purity
Silicone – widely used for biocompatibility and flexibility
EPDM – suitable for steam and sterilisation processes
FFKM – high-performance material for extreme environments
These materials ensure reliable performance and compliance in sensitive pharmaceutical applications.
Typical Applications
Our sealing solutions are used across a wide range of pharmaceutical systems:
Tablet presses and processing equipment
Filling and packaging machines
Sterilisers and autoclaves
Pumps, valves, and fluid systems
Biopharmaceutical and laboratory equipment
These applications require precision sealing to maintain product purity, process efficiency and regulatory compliance.
Why Choose Ashton Seals?
✔ Trusted UK supplier with extensive industry experience
✔ Expertise in high-compliance pharmaceutical environments
✔ Access to FDA and USP Class VI approved materials
✔ Technical support for material selection and validation
✔ Bespoke sealing solutions for specialised applications
Technical Support & Enquiries
Need help selecting the right sealing solution for your pharmaceutical application?
📞 Call: +44 (0) 1226 273700
📧 Email: ask@ashton-group.co.uk
Or contact our team for expert advice.
Frequently Asked Questions
1. What seals are used in pharmaceutical applications?
Common sealing solutions include O-rings, PTFE gaskets, inflatable seals and hygienic profiles designed for sterile and cleanroom environments.
2. What is USP Class VI certification?
USP Class VI is a strict biocompatibility standard that ensures materials are safe, non-toxic and suitable for pharmaceutical and medical use.
3. Why is FDA compliance important for seals?
FDA compliance ensures sealing materials are safe for use in applications involving drugs, medical devices and sensitive processes.
4. What materials are used in pharmaceutical seals?
Materials such as PTFE, silicone, EPDM, and FFKM are commonly used due to their chemical resistance, purity and compliance with regulatory standards.
5. Can pharmaceutical seals be customised?
Yes, sealing solutions can be engineered to meet specific process, material and regulatory requirements for pharmaceutical applications.